Smooth Endoplasmic Reticulum vs. Rough Endoplasmic Reticulum

The key difference between smooth and rough endoplasmic reticulum is that rough endoplasmic reticulum has ribosomes on its surface and thus it has rough appearance while smooth endoplasmic reticulum does not have attached ribosomes and thus it gives a smooth appearance.

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Smooth Endoplasmic Reticulum vs. Rough Endoplasmic Reticulum

The endoplasmic reticulum is found in all the cells of eukaryotes. On the basis of its function and appearance, it is divided into two types, i.e. smooth and rough type. They have some similarities and some differences in them. Rough endoplasmic reticulum has ribosomes attached with them on their surface which give them granular appearance while smooth endoplasmic reticulum do not have ribosomes attached with them and thus they have smooth, tube-like and uniform appearance.

Rough endoplasmic reticulum’s function is the production and storage of proteins while smooth endoplasmic reticulum produces, secrete and store lipids. That is why rough endoplasmic eticulum is found more in number in the cells which have extensive protein metabolism while smooth endoplasmic reticulum is found more in number in the cells which have extensive lipids metabolism.

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Rough endoplasmic reticulum is located near the plasma membrane while smooth endoplasmic reticulum is located near the nuclear membrane. Rough endoplasmic reticulum originates from nuclear membrane while smooth endoplasmic reticulum originates from rough endoplasmic reticulum when it sheds off its ribosomes. Rough endoplasmic reticulum’s inner surface is folded to give cisternae while smooth endoplasmic reticulum is made up of tubules. Rough endoplasmic reticulum is engaged in the synthesis and storage of proteins while smooth endoplasmic reticulum is engaged in the synthesis and storage of steroids, glycogen and lipids.

Pores are found on the surface of rough endoplasmic reticulum so that materials synthesized by it can pass through it but pores are absent on the surface of the smooth endoplasmic reticulum.

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Rough endoplasmic reticulum takes part in the formation of lysosomes while smooth endoplasmic reticulum takes part in the synthesis of vesicles for cis-face of Golgi body.

Contents: Difference between Smooth Endoplasmic Reticulum and Rough Endoplasmic Reticulum

Comparison Chart

BasisRough Endoplasmic ReticulumSmooth Endoplasmic Reticulum
Main difference.They have ribosomes attached with their outer surface thus they have a granular appearance.They do not have attached ribosomes on their surface and thus have a smooth appearance.
Originate from They originate from the nuclear membrane.They originate from rough endoplasmic reticulum.
LocationThey are located near the nuclear
membrane.
They are located near the plasma membrane.
Function They are involved in the synthesis and storage of proteins.They are involved in the synthesis and storage of lipids, steroids and glycogen.
Relation with another organelle They help in the formation of cis-face of the Golgi body.They help in the formation of lysosomes.
PoresThey have small pores below attached
ribosomes.
They do not have pores so materials synthesized in it cannot pass through it.
Found in cellsThey are more in number in cells that have vast protein metabolism.They are more in number in the cells which have vast lipids or steroid metabolism.
Formed ofThey are formed of cisternae.They are formed of tubules.
Higher densityTheir density is higher near nucleus and Golgi body.Their density is higher near the plasma lemma.

What is Rough Endoplasmic Reticulum?

It is an organelle which is formed of convoluted but flat sealed like sacs that are continuous with the nuclear membrane because they originate with the nuclear membrane. They are called rough because many ribosomes are attached with their outer surface which gives them granular appearance. The ribosome is the factory of protein synthesis, so the main function of rough endoplasmic
reticulum is said to be a synthesis, storage and secretion of proteins. The process of assembly of protein is called translation. Their number is greater in the cells which have extensive protein
metabolism. An average liver cell has about 13 million ribosomes attached with the RER. Although this organelle is found throughout the cell, its density is higher near the nuclear membrane.

What is Smooth Endoplasmic Reticulum?

The smooth endoplasmic reticulum is a tubular organelle which is found in the form of an interconnecting tubular network. It is called smooth because it does not have attached ribosomes on its surface. Thus it gives a smooth tube-like appearance. Its major function is to synthesize and store lipids, but it also synthesize and stores steroid hormones in endocrine glands and adrenal glands. It is also involved in glycogen metabolism in liver cells. Smooth endoplasmic reticulum also has many enzymes for detoxification.

Key Differences between Smooth Endoplasmic Reticulum and Rough Endoplasmic Reticulum

  1. Both are found in the eukaryotic cells, but rough endoplasmic reticulum has attached ribosomes with its outer surface while smooth endoplasmic reticulum does not have.
  2. Rough the endoplasmic reticulum is found more in the cells having extensive protein metabolism while smooth endoplasmic the reticulum is found more in the cells having extensive lipid metabolism
  3. Rough endoplasmic reticulum arises from the nuclear membrane while smooth type arises form a rough endoplasmic reticulum.
  4. The density of RER is greater near the nuclear membrane while that of SER is greater near the plasmalemma.
  5. Rough the endoplasmic reticulum is made up of cisternae while smooth endoplasmic reticulum is made up of tubules.
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Conclusion

The endoplasmic
reticulum is an important organelle found in the eukaryotic cells. On the basis of its appearance and presence of ribosomes, it is divided into two types, i.e. smooth endoplasmic reticulum and rough endoplasmic reticulum. It is important for biology students to differentiate between both. In the above article, we learned the clear differences between both types.

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